Ketamine (Nolvadexine), also known as glutamate enhancer, is a drug mainly used for inducing and sustaining anesthesia. It produces a state of deep sleep, amnesia, and mild pain reduction. Because it acts on the mesolimbic neurogenic pathway, ketamine has powerful effects on the nervous system without causing it side effects. The mechanism of action is by binding to GABA transaminase, stimulating the effect of GABA on neurons in the brain. Ketamine uses an important group of neurons namely neurons of the GABAergic inhibitory system which provides the basis of its actions in the central nervous system. Visit us for great deals in California Center for Ketamine Therapy-Los Angeles Ketamine Treatment For Depression
Ketamine therapy is used in the treatment of major illnesses such as chronic pain, seizures, anxiety disorders, Parkinson’s disease, menopausal syndromes, seizures, migraine headaches, and intractable pain caused by traumatic injuries, rheumatoid arthritis, cystic fibrosis, multiple sclerosis, obsessive-compulsive disorders, schizosaccharide, Parkinsonism, dysthymia, and attention deficit disorder. Ketamine has also been used in the treatment of withdrawal symptoms of patients with opiate analgesics and benzodiazepines. Ketamine has been used in low doses to increase motivation in patients with AIDS who are undergoing chemo therapy. Depression and mood disorders have also responded favorably to low doses of ketamine. Ketamine has also been used to treat patients with depression and bipolar disorder who respond to at least one type of antidepressant.
During anesthetic procedures, ketamine may be administered intravenously in a variety of methods including an Intravenous (IV) infusion, Intraventricular (IV) infusion, or inhalation. IV and inhalation infusion methods of administration have been approved by FDA in the past few years, but their use remains under debate for safety concerns. Intravenous infusion methods involve the administration of the drug through the vein, whereas intraventricular infusion methods use a pump that delivers the drug into the airways. Studies indicate that long-term use of ketamine therapy may result in some mild anesthetic complications. However, long-term studies have not been conducted comparing IV and inhalation infusions with placebo.